About CancerGxSuite

CancerGxSuite is an open-source software ecosystem that expands to multiple domains (immortalized cell lines, patient-derived organoids, and patient-derived xenografts), to build an foundational framework of preclinical research in oncology, toxicology, and radiology. It allows the cancer research community to identify the molecular features of cancer cells predictive of pharmacological and radiation treatments and related toxicities.

More specifically, CancerGxSuite provides a set of functions and classes in the open-source programming language R for domain-specific scientific software libraries, namely PharmacoGx, ToxicoGx, RadioGx, and Xeva. CoreGx abstracts shared functionality for the suite of software packages, allowing for standardized modular data structures, and functions for fitting and plotting of treatment response, and making data amenable to statistical and machine learning analysis. The broader CancerGxSuite ecosystem includes web-portal access to the underlying data (PharmacoDB, ToxicoDB, and XevaDB), as well as a tool for building new pharmacogenomic datasets in a transparent and reproducible manner (ORCESTRA).